GID4
The glucose-induced degradation protein 4 homologue (GID4), a substrate recognition component of the C-terminal to LisH (CTLH) E3 ligase complex. GID4 serves as the substrate receptor. It can recognize N-terminal proline degradation signal (Pro/N degron) as well as specific hydrophobic residues, guiding the substrate proteins to the 26S proteasome for degradation[1].
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GID4 Related Products (1)
Related Products (1)
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PFI-7
0 ImagesCat. No.: HY-D2259CAS No.: 2910938-58-6PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation.
